Pemetrexed under brand name Alimta is a form drug manufactured by Eli Lily and Company. Its purpose to treat maligant pleural mesothelioma and non small cell lung cancer.
In 2004, United States Food and Drug Administration approved the drug for the treatment of malignant pleural mesothelioma (MPM), in combination with cisplatin. In 2008 FDA approved as first line treatment in combination with cisplatin, against of locally-advanced and metastatic non-small cell lung cancer.
Maligant pleural mesothelioma is relatively a mainstream cancer, with only an approximate 2,000 new cases each year. Whose incidence is expected to increase in the, Western Europe, United Kingdom and Australia over the next 20 years. MPM is usually linked previously exposure to asbestos. When asbestos fibres are swallowed or inhaled, they can cause scarring of the lung tissues, cancer of the bronchial tree and sometimes cancers in the peritoneum and pleura.
To treat malignant pleural mesothelioma, generally, patients are encouraged to take a drug known as Pemetrexed. MTA, anti-folates, Pemetrexed lends its success to fighting MPM through its ability to block folic acid from reaching cancer cells. Pemetrexed prevents no growth of the cancer cells that lead to MPM growth. There is no standard chemotherapy treatment for MPM. Pemetrexed in combination with cisplatin is the only chemotherapy regimen that is currently licensed for this indication. However, a variety of combination and single-agent regimens such as the mitomycin C, vinblastine and cisplatin combination (MVP) or vinorelbine are used. Pemetrexed costs about £800 for a 500-mg
In 2003, Journal of Clinical Oncology, Vogelzang et al release a 6 report , randomized trial that compared cisplatin alone to cisplatin plus pemetrexed, a new anti folate, in patients with unresectable MPM. The combination chemotherapy was well tolerated and was associated with a significantly better progression-free and overall survival. Other researcher’s finding that shown to experience an increased life span by up to three years when battling malignant pleural mesothelioma.
Common side effect associated with Pemetrexed included vomiting, nausea, neutropenia and fatigue. Somehow, mucositis , skin rash and liver function also has been reported.
In fact, all patients with MSM are selected to dose of Pemetrexed in lung cancer treatment.Generally, patients with shingles, heart disease, kidney and liver disease are not allowed to using Pemetrexed in MSM treatment.
In fact, all patients with MSM are selected to use of Pemetrexed in lung cancer treatment, Generally, patients with shingles, heart disease, kidney and liver disease are not allowed to using Pemetrexed in MSM treatment.
By: koay lye chin
Pemetrexed (lung cancer treatment) used in treatmenting for maligant pleural mesothelioma
Biological Therapy For Cancer Treatment In India At Affordable Cost
Biological Therapy
What is biological therapy?
Biological therapy is a type of treatment that works with your immune system. It can help fight cancer or help control side effects (how your body reacts to the drugs you are taking) from other cancer treatments like chemotherapy.
What is the difference between biological therapy and chemotherapy ?
Biological therapy and chemotherapy are both treatments that fight cancer. While they may seem alike, they work in different ways. Biological therapy helps your immune system fight cancer. Chemotherapy attacks the cancer cells directly.
How does biological therapy fight cancer ?
Doctors are not sure how biological therapy helps your immune system fight cancer.
But they think it may : -
Stop or slow the growth of cancer cells. Make it easier for your immune system to destroy, or get rid of, cancer cells. Keep cancer from spreading to other parts of your body.
What is my immune system and how does it work ?
Your immune system includes your spleen, lymph nodes, tonsils, bone marrow, and white blood cells. These all help protect you from getting infections and diseases.
When your immune system works the way it should, it can tell the difference between “good” cells that keep you healthy and “bad” cells that make you sick. But sometimes this doesn’t happen. Doctors are doing research to learn why some immune systems don’t fight off diseases like cancer…
What are cancer vaccines?
Cancer vaccines are a form of biological therapy. While other vaccines (like ones for measles or mumps) are given before you get sick, cancer vaccines are given after you have cancer. Cancer vaccines may help your body fight the cancer and keep it from coming back.
Doctors are learning more all the time about cancer vaccines. They are now doing research about how cancer vaccines can help people diagnosed with melanoma, lymphoma, and kidney, breast, ovarian, prostate, colon, and rectal cancers…
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